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Molecular differences in transition zone and peripheral zone prostate tumors

Prostate tumors arise primarily in the peripheral zone (PZ) of the prostate, but 20–30% arise in the transition zone (TZ). Zone of origin may have prognostic value or reflect distinct molecular subtypes; however, it can be difficult to determine in practice. Using whole-genome gene expression, we bu...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Sinnott, Jennifer A., Rider, Jennifer R., Carlsson, Jessica, Gerke, Travis, Tyekucheva, Svitlana, Penney, Kathryn L., Sesso, Howard D., Loda, Massimo, Fall, Katja, Stampfer, Meir J., Mucci, Lorelei A., Pawitan, Yudi, Andersson, Sven-Olof, Andrén, Ove
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572920/
https://ncbi.nlm.nih.gov/pubmed/25870172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv051
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