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Targeted Disruption of the β(2)-Microglobulin Gene Minimizes the Immunogenicity of Human Embryonic Stem Cells
Human embryonic stem cells (hESCs) are a promising source of cells for tissue regeneration, yet histoincompatibility remains a major challenge to their clinical application. Because the human leukocyte antigen class I (HLA-I) molecules are the primary mediators of immune rejection, we hypothesized t...
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| Publicado no: | Stem Cells Transl Med |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AlphaMed Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4572902/ https://ncbi.nlm.nih.gov/pubmed/26285657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0049 |
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