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GnT1IP-L specifically inhibits MGAT1 in the Golgi via its luminal domain
Mouse GnT1IP-L, and membrane-bound GnT1IP-S (MGAT4D) expressed in cultured cells inhibit MGAT1, the N-acetylglucosaminyltransferase that initiates the synthesis of hybrid and complex N-glycans. However, it is not known where in the secretory pathway GnT1IP-L inhibits MGAT1, nor whether GnT1IP-L inhi...
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| 發表在: | eLife |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications, Ltd
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4572887/ https://ncbi.nlm.nih.gov/pubmed/26371870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08916 |
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