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Roles of the six peptide-binding pockets of the HLA-A2 molecule in allorecognition by human cytotoxic T-cell clones.

To evaluate the contribution of the major histocompatibility complex class I pockets to the binding of self-peptides recognized by alloreactive cytotoxic T-lymphocyte (CTL) clones, we have constructed an extensive library of HLA-A2 mutants with different amino acid substitutions in each of the six p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Matsui, M, Hioe, C E, Frelinger, J A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45726/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7678462/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.2.674
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