POD-1/TCF21 Reduces SHP Expression, Affecting LRH-1 Regulation and Cell Cycle Balance in Adrenocortical and Hepatocarcinoma Tumor Cells

POD-1/TCF21 may play a crucial role in adrenal and gonadal homeostasis and represses Sf-1/SF-1 expression in adrenocortical tumor cells. SF-1 and LRH-1 are members of the Fzt-F1 subfamily of nuclear receptors. LRH-1 is involved in several biological processes, and both LRH-1 and its repressor SHP ar...

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Vydáno v:Biomed Res Int
Hlavní autoři: França, Monica Malheiros, Ferraz-de-Souza, Bruno, Lerario, Antonio Marcondes, Fragoso, Maria Candida Barisson Villares, Lotfi, Claudimara Ferini Pacicco
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572413/
https://ncbi.nlm.nih.gov/pubmed/26421305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/841784
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