Protective Effect of Tat PTD-Hsp27 Fusion Protein on Tau Hyperphosphorylation Induced by Okadaic Acid in the Human Neuroblastoma Cell Line SH-SY5Y

Alzheimer’s disease (AD) is an age-related disorder that causes a loss of brain function. Hyperphosphorylation of tau and the subsequent formation of intracellular neurofibrillary tangles (NFTs) are implicated in the pathogenesis of AD. Hyperphosphorylated tau accumulates into insoluble paired helic...

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Vydáno v:Cell Mol Neurobiol
Hlavní autoři: Choi, Sunghyun, Oh, Jae Hoon, Kim, Hyeseon, Nam, So Hee, Shin, Jeehae, Park, Jong-Sang
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572059/
https://ncbi.nlm.nih.gov/pubmed/25990227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-015-0199-1
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