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Strategies for fine-mapping complex traits

Genome-wide association studies (GWAS) have identified thousands of robust and replicable genetic associations for complex disease. However, the identification of the causal variants that underlie these associations has been more difficult. This problem of fine-mapping association signals predates G...

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Publicat a:Hum Mol Genet
Autors principals: Spain, Sarah L., Barrett, Jeffrey C.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572002/
https://ncbi.nlm.nih.gov/pubmed/26157023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv260
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