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Coalescent-Based Association Mapping and Fine Mapping of Complex Trait Loci
We outline a general coalescent framework for using genotype data in linkage disequilibrium-based mapping studies. Our approach unifies two main goals of gene mapping that have generally been treated separately in the past: detecting association (i.e., significance testing) and estimating the locati...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Genetics Society of America
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1449137/ https://ncbi.nlm.nih.gov/pubmed/15489534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.031799 |
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