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Non-coding genetic variants in human disease

Genetic variants, including single-nucleotide variants (SNVs) and copy number variants (CNVs), in the non-coding regions of the human genome can play an important role in human traits and complex diseases. Most of the genome-wide association study (GWAS) signals map to non-coding regions and potenti...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Hum Mol Genet
Main Authors: Zhang, Feng, Lupski, James R.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572001/
https://ncbi.nlm.nih.gov/pubmed/26152199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv259
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