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Receptor tyrosine kinase mutations in developmental syndromes and cancer: two sides of the same coin
Receptor tyrosine kinases (RTKs) are a family of ligand-binding cell surface receptors that regulate a wide range of essential cellular activities, including proliferation, differentiation, cell-cycle progression, survival and apoptosis. As such, these proteins play an important role during developm...
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| Veröffentlicht in: | Hum Mol Genet |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4572000/ https://ncbi.nlm.nih.gov/pubmed/26152202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv254 |
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