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Receptor tyrosine kinase mutations in developmental syndromes and cancer: two sides of the same coin

Receptor tyrosine kinases (RTKs) are a family of ligand-binding cell surface receptors that regulate a wide range of essential cellular activities, including proliferation, differentiation, cell-cycle progression, survival and apoptosis. As such, these proteins play an important role during developm...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: McDonell, Laura M., Kernohan, Kristin D., Boycott, Kym M., Sawyer, Sarah L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572000/
https://ncbi.nlm.nih.gov/pubmed/26152202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv254
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