Dynamic Arginine Methylation of Tumor Necrosis Factor (TNF) Receptor-associated Factor 6 Regulates Toll-like Receptor Signaling

Arginine methylation is a common post-translational modification, but its role in regulating protein function is poorly understood. This study demonstrates that, TNF receptor-associated factor 6 (TRAF6), an E3 ubiquitin ligase involved in innate immune signaling, is regulated by reversible arginine...

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Pubblicato in:J Biol Chem
Autori principali: Tikhanovich, Irina, Kuravi, Sudhakiranmayi, Artigues, Antonio, Villar, Maria T., Dorko, Kenneth, Nawabi, Atta, Roberts, Benjamin, Weinman, Steven A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571974/
https://ncbi.nlm.nih.gov/pubmed/26221041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.653543
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