Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases

Tumor vessel normalization has been proposed as a therapeutic paradigm. However, normal microvessels are hierarchical and vasoreactive with single file transit of red blood cells through capillaries. Such a network has not been identified in malignant tumors. We tested whether the chaotic tumor micr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yin, Hao, Frontini, Matthew J., Arpino, John-Michael, Nong, Zengxuan, O'Neil, Caroline, Xu, Yiwen, Balint, Brittany, Ward, Aaron D., Chakrabarti, Subrata, Ellis, Christopher G., Gros, Robert, Pickering, J. Geoffrey
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571963/
https://ncbi.nlm.nih.gov/pubmed/26183774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.652222
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