Activin Regulates Self-renewal and Differentiation of Trophoblast Stem Cells by Down-regulating the X Chromosome Gene Bcor

The development of a functional placenta is largely dependent upon proper proliferation and differentiation of trophoblast stem cells (TSCs). Activin signaling has long been regarded to play important roles during this process, but the exact mechanism is largely unknown. Here, we demonstrate that th...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhu, Gaoyang, Fei, Teng, Li, Zhongwei, Yan, Xiaohua, Chen, Ye-Guang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571955/
https://ncbi.nlm.nih.gov/pubmed/26221038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.674127
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