The functional significance of DNA sequence structure in a site-specific genetic recombination reaction.

A series of sequence changes in the spacer region of the FLP recombination target (FRT) site are presented which drastically reduce site function without affecting recognition by the FLP protein. The effects follow a pattern which indicates that two structural features of the FRT site are essential...

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Bibliographic Details
Main Authors: Umlauf, S W, Cox, M M
Format: Artigo
Language:Inglês
Published: 1988
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC457177/
https://ncbi.nlm.nih.gov/pubmed/3169007
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