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Etomidate Impairs Long-Term Potentiation In Vitro by Targeting α5-Subunit Containing GABA(A) Receptors on Nonpyramidal Cells
Previous experiments using genetic and pharmacological manipulations have provided strong evidence that etomidate impairs synaptic plasticity and memory by modulating α5-subunit containing GABA(A) receptors (α5-GABA(A)Rs). Because α5-GABA(A)Rs mediate tonic inhibition (TI) in hippocampal CA1 pyramid...
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| Veröffentlicht in: | J Neurosci |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4571505/ https://ncbi.nlm.nih.gov/pubmed/26134653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0315-15.2015 |
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