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Post-zygotic Point Mutations Are an Underrecognized Source of De Novo Genomic Variation
De novo mutations are recognized both as an important source of genetic variation and as a prominent cause of sporadic disease in humans. Mutations identified as de novo are generally assumed to have occurred during gametogenesis and, consequently, to be present as germline events in an individual....
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| Publicado no: | Am J Hum Genet |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4571017/ https://ncbi.nlm.nih.gov/pubmed/26054435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.05.008 |
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