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Granzyme B-expressing neutrophils correlate with bacterial load in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques

The role of neutrophils in tuberculosis (TB), and whether neutrophils express granzyme B (grzB), a pro-apoptotic enzyme associated with cytotoxic T cells, is controversial. We examined neutrophils in peripheral blood (PB) and lung granulomas of Mycobacterium tuberculosis-infected cynomolgus macaques...

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Detalhes bibliográficos
Publicado no:Cell Microbiol
Main Authors: Mattila, Joshua T., Maiello, Pauline, Sun, Tao, Via, Laura E., Flynn, JoAnne L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570831/
https://ncbi.nlm.nih.gov/pubmed/25653138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12428
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