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In Situ Study of Abundant Expression of Proinflammatory Chemokines and Cytokines in Pulmonary Granulomas That Develop in Cynomolgus Macaques Experimentally Infected with Mycobacterium tuberculosis

Tuberculosis remains a major public health problem worldwide. Chemokines and cytokines organize and direct infiltrating cells to sites of infection, and these molecules likely play crucial roles in granuloma formation and maintenance. To address this issue, we used in situ hybridization (ISH) to mea...

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Bibliographic Details
Main Authors: Fuller, Craig L., Flynn, JoAnne L., Reinhart, Todd A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC308896/
https://ncbi.nlm.nih.gov/pubmed/14638792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.7023-7034.2003
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