ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry

Interferon stimulated genes (ISGs) target viruses at various stages of their infectious life cycles, including at the earliest stage of viral entry. Here we identify ArfGAP with dual pleckstrin homology (PH) domains 2 (ADAP2) as a gene upregulated by type I IFN treatment in a STAT1-dependent manner....

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Publicado en:PLoS Pathog
Autores principales: Shu, Qian, Lennemann, Nicholas J., Sarkar, Saumendra N., Sadovsky, Yoel, Coyne, Carolyn B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570769/
https://ncbi.nlm.nih.gov/pubmed/26372645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005150
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