ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry

Interferon stimulated genes (ISGs) target viruses at various stages of their infectious life cycles, including at the earliest stage of viral entry. Here we identify ArfGAP with dual pleckstrin homology (PH) domains 2 (ADAP2) as a gene upregulated by type I IFN treatment in a STAT1-dependent manner....

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Shu, Qian, Lennemann, Nicholas J., Sarkar, Saumendra N., Sadovsky, Yoel, Coyne, Carolyn B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570769/
https://ncbi.nlm.nih.gov/pubmed/26372645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005150
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