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Roles of Klf5 Acetylation in the Self-Renewal and the Differentiation of Mouse Embryonic Stem Cells

Transcription factor Krüppel-like factor 5 (Klf5) plays important roles in the formation of the inner cell mass (ICM) and the trophectoderm during embryogenesis, as well as the self-renewal and the differentiation of mouse embryonic stem cells (ESCs). Acetylation of KLF5 has been shown to reverse th...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Zhao, Tong, Liu, Chang, Chen, Lingyi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570665/
https://ncbi.nlm.nih.gov/pubmed/26372456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138168
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