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Variants of human tissue-type plasminogen activator that lack specific structural domains of the heavy chain.

The heavy chain of tissue plasminogen activator (t-PA) consists of four domains [finger, epidermal-growth-factor (EGF)-like, kringle 1 and kringle 2] that are homologous to similar domains present in other proteins. To assess the contribution of each of the domains to the biological properties of th...

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Autors principals: Gething, M J, Adler, B, Boose, J A, Gerard, R D, Madison, E L, McGookey, D, Meidell, R S, Roman, L M, Sambrook, J
Format: Artigo
Idioma:Inglês
Publicat: 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC457063/
https://ncbi.nlm.nih.gov/pubmed/2846282
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