Variants of human tissue-type plasminogen activator that lack specific structural domains of the heavy chain.

The heavy chain of tissue plasminogen activator (t-PA) consists of four domains [finger, epidermal-growth-factor (EGF)-like, kringle 1 and kringle 2] that are homologous to similar domains present in other proteins. To assess the contribution of each of the domains to the biological properties of th...

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Pubblicato in:	EMBO J
Autori principali:	Gething, M J, Adler, B, Boose, J A, Gerard, R D, Madison, E L, McGookey, D, Meidell, R S, Roman, L M, Sambrook, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC457063/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2846282/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03127.x
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