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A unique binding mode of the eukaryotic translation initiation factor 4E for guiding the design of novel peptide inhibitors
The interaction between the eukaryotic translation initiation factor 4E (eIF4E) and eIF4E binding proteins (4E-BP) is a promising template for the inhibition of eIF4E and the treatment of diseases such as cancer and a spectrum of autism disorders, including the Fragile X syndrome (FXS). Here, we rep...
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| Publicat a: | Protein Sci |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley & Sons, Ltd
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4570532/ https://ncbi.nlm.nih.gov/pubmed/26013047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2708 |
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