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Changes in drug sensitivity of human immunodeficiency virus type 1 during therapy with azidothymidine, dideoxycytidine, and dideoxyinosine: an in vitro comparative study.

Human immunodeficiency virus type 1 (HIV-1) strains were isolated from nine patients before and after prolonged therapy with either an alternating regimen of 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (ddC) (AZT/ddC) or 2',3'-dideoxyinosine (ddI) alone. All strains obtained from four...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Shirasaka, T, Yarchoan, R, O'Brien, M C, Husson, R N, Anderson, B D, Kojima, E, Shimada, T, Broder, S, Mitsuya, H
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1993
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45703/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8380641/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.2.562
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