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New role of Interleukin-10 in enhancing the antitumor efficacy of oncolytic vaccinia virus for treatment of pancreatic cancer

Although the profile of safety of tumor-targeted oncolytic virus (TOV) is encouraging, the antitumor efficacy of TOV alone is disappointing. Interleukin-10 (IL-10) plays an important role in carcinogenesis and anti-virus immunity. Here we report that tumor-targeted oncolytic vaccinia virus (VV) arme...

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Vydáno v:Oncoimmunology
Hlavní autoři: Chard, Louisa S, Lemoine, Nicholas R, Wang, Yaohe
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570121/
https://ncbi.nlm.nih.gov/pubmed/26405610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1038689
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