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Thioredoxin induces Tregs to generate an immunotolerant tumor microenvironment in metastatic melanoma

Metastatic melanoma is a highly aggressive cancer that is very difficult to treat. Additionally, the antitumor immune reaction of melanoma is still unclear. Here we demonstrate an association between the expression and secretion of the antioxidant protein thioredoxin (TRX) and increasing tumor stage...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Wang, Xiaogang, Dong, Haisheng, Li, Qi, Li, Yingxian, Hong, An
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570104/
https://ncbi.nlm.nih.gov/pubmed/26405597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1027471
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