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Postnatal β-cell maturation is associated with islet-specific microRNA changes induced by nutrient shifts at weaning

Glucose-induced insulin secretion is an essential function of pancreatic β-cells that is partially lost in individuals affected by Type 2 diabetes. This unique property of β-cells is acquired through a poorly understood postnatal maturation process involving major modifications in gene expression pr...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jacovetti, Cécile, Matkovich, Scot J., Rodriguez-Trejo, Adriana, Guay, Claudiane, Regazzi, Romano
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569696/
https://ncbi.nlm.nih.gov/pubmed/26330140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9084
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