Drosophila Eye Model to Study Neuroprotective Role of CREB Binding Protein (CBP) in Alzheimer’s Disease

BACKGROUND: The progressive neurodegenerative disorder Alzheimer’s disease (AD) manifests as loss of cognitive functions, and finally leads to death of the affected individual. AD may result from accumulation of amyloid plaques. These amyloid plaques comprising of amyloid-beta 42 (Aβ42) polypeptides...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cutler, Timothy, Sarkar, Ankita, Moran, Michael, Steffensmeier, Andrew, Puli, Oorvashi Roy, Mancini, Greg, Tare, Meghana, Gogia, Neha, Singh, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569556/
https://ncbi.nlm.nih.gov/pubmed/26367392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137691
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