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RhoGAP18B Isoforms Act on Distinct Rho-Family GTPases and Regulate Behavioral Responses to Alcohol via Cofilin

Responses to the effects of ethanol are highly conserved across organisms, with reduced responses to the sedating effects of ethanol being predictive of increased risk for human alcohol dependence. Previously, we described that regulators of actin dynamics, such as the Rho-family GTPases Rac1, Rho1,...

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Publicat a:PLoS One
Autors principals: Ojelade, Shamsideen A., Acevedo, Summer F., Kalahasti, Geetha, Rodan, Aylin R., Rothenfluh, Adrian
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569326/
https://ncbi.nlm.nih.gov/pubmed/26366560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137465
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