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The Myopic-Ubpy-Hrs nexus enables endosomal recycling of Frizzled

Endosomal trafficking of signaling proteins plays an essential role in cellular homeostasis. The seven-pass transmembrane protein Frizzled (Fz) is a critical component of Wnt signaling. Although Wnt signaling is proposed to be regulated by endosomal trafficking of Fz, the molecular events that enabl...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Pradhan-Sundd, Tirthadipa, Verheyen, Esther M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569321/
https://ncbi.nlm.nih.gov/pubmed/26224310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-02-0086
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