Tumor necrosis factor–related apoptosis-inducing ligand induces the expression of proinflammatory cytokines in macrophages and re-educates tumor-associated macrophages to an antitumor phenotype

Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) is a promising candidate for cancer therapy, because it can induce apoptosis in various tumor cells but not in most normal cells. Although it is well known that TRAIL and its receptors are expressed in many types of normal cells, includ...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Gao, Jing, Wang, Dongsheng, Liu, Dan, Liu, Min, Ge, Yehua, Jiang, Minghong, Liu, Yanxin, Zheng, Dexian
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569310/
https://ncbi.nlm.nih.gov/pubmed/26224317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-04-0209
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