Tumor necrosis factor–related apoptosis-inducing ligand induces the expression of proinflammatory cytokines in macrophages and re-educates tumor-associated macrophages to an antitumor phenotype

Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) is a promising candidate for cancer therapy, because it can induce apoptosis in various tumor cells but not in most normal cells. Although it is well known that TRAIL and its receptors are expressed in many types of normal cells, includ...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Gao, Jing, Wang, Dongsheng, Liu, Dan, Liu, Min, Ge, Yehua, Jiang, Minghong, Liu, Yanxin, Zheng, Dexian
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569310/
https://ncbi.nlm.nih.gov/pubmed/26224317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-04-0209
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