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Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier

Desmosomal cadherins mediate intercellular adhesion and control epithelial homeostasis. Recent studies show that proteinases play an important role in the pathobiology of cancer by targeting epithelial intercellular junction proteins such as cadherins. Here we describe the proinflammatory cytokine-i...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Kamekura, Ryuta, Nava, Porfirio, Feng, Mingli, Quiros, Miguel, Nishio, Hikaru, Weber, Dominique A., Parkos, Charles A., Nusrat, Asma
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569309/
https://ncbi.nlm.nih.gov/pubmed/26224314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-03-0147
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