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Changes in neuronal CycD/Cdk4 activity affect aging, neurodegeneration, and oxidative stress
Mitochondrial dysfunction has been implicated in human diseases, including cancer, and proposed to accelerate aging. The Drosophila Cyclin-dependent protein kinase complex cyclin D/cyclin-dependent kinase 4 (CycD/Cdk4) promotes cellular growth by stimulating mitochondrial biogenesis. Here, we examin...
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| Publicat a: | Aging Cell |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley & Sons, Ltd
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4568977/ https://ncbi.nlm.nih.gov/pubmed/26219626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12376 |
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