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The Drosophila Cyclin D–Cdk4 complex promotes cellular growth
Mammalian cyclin D–Cdk4 complexes have been characterized as growth factor-responsive cell cycle regulators. Their levels rise upon growth factor stimulation, and they can phosphorylate and thus neutralize Retinoblastoma (Rb) family proteins to promote an E2F-dependent transcriptional program and S-...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302080/ https://ncbi.nlm.nih.gov/pubmed/10970848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.17.4543 |
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