Regulation of p53 during senescence in normal human keratinocytes

p53, the guardian of the genome, is a tumor suppressor protein and critical for the genomic integrity of the cells. Many studies have shown that intracellular level of p53 is enhanced during replicative senescence in normal fibroblasts, and the enhanced level of p53 is viewed as the cause of senesce...

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Publicat a:Aging Cell
Autors principals: Kim, Reuben H, Kang, Mo K, Kim, Terresa, Yang, Paul, Bae, Susan, Williams, Drake W, Phung, Samantha, Shin, Ki-Hyuk, Hong, Christine, Park, No-Hee
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568971/
https://ncbi.nlm.nih.gov/pubmed/26138448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12364
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