Regulation of p53 during senescence in normal human keratinocytes

p53, the guardian of the genome, is a tumor suppressor protein and critical for the genomic integrity of the cells. Many studies have shown that intracellular level of p53 is enhanced during replicative senescence in normal fibroblasts, and the enhanced level of p53 is viewed as the cause of senesce...

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Enregistré dans:
Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Kim, Reuben H, Kang, Mo K, Kim, Terresa, Yang, Paul, Bae, Susan, Williams, Drake W, Phung, Samantha, Shin, Ki-Hyuk, Hong, Christine, Park, No-Hee
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Ltd 2015
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568971/
https://ncbi.nlm.nih.gov/pubmed/26138448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12364
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