Regulation of p53 during senescence in normal human keratinocytes

p53, the guardian of the genome, is a tumor suppressor protein and critical for the genomic integrity of the cells. Many studies have shown that intracellular level of p53 is enhanced during replicative senescence in normal fibroblasts, and the enhanced level of p53 is viewed as the cause of senesce...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging Cell
Prif Awduron: Kim, Reuben H, Kang, Mo K, Kim, Terresa, Yang, Paul, Bae, Susan, Williams, Drake W, Phung, Samantha, Shin, Ki-Hyuk, Hong, Christine, Park, No-Hee
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley & Sons, Ltd 2015
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568971/
https://ncbi.nlm.nih.gov/pubmed/26138448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12364
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