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Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1

Aging constitutes a significant risk factor for fibrosis, and idiopathic pulmonary fibrosis (IPF) is characteristically associated with advancing age. We propose that age-dependent defects in the quality of protein and cellular organelle catabolism may be causally related to pulmonary fibrosis. Our...

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Publicado en:Aging Cell
Autores principales: Sosulski, Meredith L, Gongora, Rafael, Danchuk, Svitlana, Dong, Chunmin, Luo, Fayong, Sanchez, Cecilia G
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons, Ltd 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568965/
https://ncbi.nlm.nih.gov/pubmed/26059457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12357
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