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A Data Analysis Pipeline Accounting for Artifacts in Tox21 Quantitative High-Throughput Screening Assays

A main goal of the U.S. Tox21 program is to profile a 10K-compound library for activity against a panel of stress-related and nuclear receptor signaling pathway assays using a quantitative high-throughput screening (qHTS) approach. However, assay artifacts, including nonreproducible signals and assa...

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Bibliografische gegevens
Gepubliceerd in:J Biomol Screen
Hoofdauteurs: Hsieh, Jui-Hua, Sedykh, Alexander, Huang, Ruili, Xia, Menghang, Tice, Raymond R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568956/
https://ncbi.nlm.nih.gov/pubmed/25904095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057115581317
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