Urokinase receptor and CXCR4 are regulated by common microRNAs in leukaemia cells

The urokinase-type plasminogen activator (uPA) receptor (uPAR) focuses uPA proteolytic activity on the cell membrane, promoting localized degradation of extracellular matrix (ECM), and binds vitronectin (VN), mediating cell adhesion to the ECM. uPAR-bound uPA and VN induce proteolysis-independent in...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Alfano, Daniela, Gorrasi, Anna, Li Santi, Anna, Ricci, Patrizia, Montuori, Nunzia, Selleri, Carmine, Ragno, Pia
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568930/
https://ncbi.nlm.nih.gov/pubmed/26082201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12617
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