Identification of uPAR Variants Acting as ceRNAs in Leukaemia Cells

The 3′untranslated region (3′UTR) of the urokinase (uPA) receptor (uPAR) mRNA can act as a competitive endogenous RNA (ceRNA) in acute myeloid leukaemia (AML) cells, promoting the expression of pro-tumoral targets, including uPAR. Here, we identified three variants of uPAR mRNA containing the 3′UTR,...

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Autores principales: Mariaevelina Alfieri, Anna Li Santi, Luigia Meo, Valentina Giudice, Carmine Selleri, Pia Ragno
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2022-04-01
Colección:Cancers
Materias:
uPAR
urokinase receptor
ceRNA
AML
microRNA
Acceso en línea:https://www.mdpi.com/2072-6694/14/8/1980
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