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Redox status of high-mobility group box 1 performs a dual role in angiogenesis of colorectal carcinoma
During inflammation, high-mobility group box 1 in reduced all-thiol form (at-HMGB1) takes charge of chemoattractant activity, whereas only disulfide-HMGB1 (ds-HMGB1) has cytokine activity. Also as pro-angiogenic inducer, the role of HMGB1 in different redox states has never been defined in tumour an...
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| Publicado no: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4568917/ https://ncbi.nlm.nih.gov/pubmed/26099505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12577 |
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