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Telomerase RNA stem terminus element affects template boundary element function, telomere sequence, and shelterin binding

The stem terminus element (STE), which was discovered 13 y ago in human telomerase RNA, is required for telomerase activity, yet its mode of action is unknown. We report that the Schizosaccharomyces pombe telomerase RNA, TER1 (telomerase RNA 1), also contains a STE, which is essential for telomere m...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Webb, Christopher J., Zakian, Virginia A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568702/
https://ncbi.nlm.nih.gov/pubmed/26305931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503157112
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