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IFN-γ ameliorates autoimmune encephalomyelitis by limiting myelin lipid peroxidation

Evidence has suggested both a pathogenic and a protective role for the proinflammatory cytokine IFN-γ in experimental autoimmune encephalomyelitis (EAE). However, the mechanisms underlying the protective role of IFN-γ in EAE have not been fully resolved, particularly in the context of CNS antigen-pr...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Sosa, Rebecca A., Murphey, Cathi, Robinson, Rachel R., Forsthuber, Thomas G.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568689/
https://ncbi.nlm.nih.gov/pubmed/26305941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505955112
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