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On the predictive utility of animal models of osteoarthritis

Animal models of osteoarthritis are extensively used for investigating disease pathways and for preclinical testing of novel therapies. Their predictive utility, however, has often been questioned, mainly because preclinical efficacy of novel therapeutics is poorly translated in clinical trials. In...

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Bibliographische Detailangaben
Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Malfait, Anne-Marie, Little, Christopher B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568581/
https://ncbi.nlm.nih.gov/pubmed/26364707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0747-6
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