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On the predictive utility of animal models of osteoarthritis

Animal models of osteoarthritis are extensively used for investigating disease pathways and for preclinical testing of novel therapies. Their predictive utility, however, has often been questioned, mainly because preclinical efficacy of novel therapeutics is poorly translated in clinical trials. In...

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Detaylı Bibliyografya
Yayımlandı:Arthritis Res Ther
Asıl Yazarlar: Malfait, Anne-Marie, Little, Christopher B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568581/
https://ncbi.nlm.nih.gov/pubmed/26364707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0747-6
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