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Leukocyte function-associated antigen-1 deficiency impairs responses to polymicrobial sepsis

AIM: To determine the role of leukocyte function-associated antigen-1 (LFA-1) in polymicrobial sepsis model in mice. METHODS: Cecal ligation and puncture model was used to study polymicrobial sepsis in wild type and LFA-1 knockout (KO) (= CD11a KO) mice. Their survivals were examined. Neutrophil rec...

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Detalhes bibliográficos
Publicado no:World J Clin Cases
Main Authors: Liu, Jia-Ren, Han, Xiaohui, Soriano, Sulpicio G, Yuki, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568529/
https://ncbi.nlm.nih.gov/pubmed/26380827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12998/wjcc.v3.i9.793
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