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Interrogation of the intersubunit interface of the open Hv1 proton channel with a probe of allosteric coupling

The Hv1 voltage-gated proton channel is a dimeric complex consisting of two voltage-sensing domains (VSDs), each containing a gated proton permeation pathway. Dimerization is controlled by a cytoplasmic coiled-coil domain. The transitions from the closed to the open state in the two VSDs are known t...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Hong, Liang, Singh, Vikrant, Wulff, Heike, Tombola, Francesco
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568520/
https://ncbi.nlm.nih.gov/pubmed/26365828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14077
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