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Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives
The voltage-gated proton channel Hv1 plays important roles in proton extrusion, pH homeostasis, and production of reactive oxygen species in a variety of cell types. Excessive Hv1 activity increases proliferation and invasiveness in cancer cells and worsens brain damage in ischemic stroke. The chann...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4103315/ https://ncbi.nlm.nih.gov/pubmed/24912149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1324012111 |
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